The pharmacological effects of bamboo
Pharmacological effects
Calming
Xu Changqing extract (concentrated by decocting, adding ethanol to remove precipitate, which does not contain phytol)
Intraperitoneal Injection of mice can significantly reduce spontaneous activity, quietness, and drooping of the eyelids, and respond to external stimuli. The effect lasts for more than 60 minutes. But does not prolong the sleep time of barbiturates.
Analgesic effect
The above extract was injected intraperitoneally to the mice and analgesia occurred within 10 minutes and did not disappear after 60 minutes. Clinical studies showed that: Paeonol was dissolved in peanut oil and made into injections to treat more than 20 cases of pain, with an effective rate of 83%. Among them, rheumatic arthralgia was effective, and renal colic, toothache, and sella tumor were observed. The analgesic effect of pain is satisfactory, but the pain caused by vasculitis and osteomyelitis is not effective. Mouse hot plate pain test also showed that Xu Changqing has analgesic effect.
Effects on the cardiovascular system
Xu Changqing can slow down the heart rate of normal animals. Electrocardiogram observation showed that rabbits were intravenously injected with Xu Changqing. Rats received intraperitoneal injection of prolonged RR intervals, and PR intervals and T wave did not change significantly. Xu Changqing can significantly increase the uptake of Rb86 in mouse myocardium, which can be considered to increase coronary blood flow, improve myocardial metabolism, and relieve myocardial ischemia. Continuous administration of Xu Changqing for 7 days could not prevent the change of acute myocardial hypoxia electrocardiogram induced by intravenous injection of pituitrin to rabbits. Animal experiments show that: Xu Changqing can reduce blood pressure in dogs, rabbits and rats. With Xuchangqing, which contains no paeonol, the blood pressure of anesthetized animals is still rapidly and temporarily reduced. Therefore, besides paeonol, Xu Changqing still contains other antihypertensive components.
Effect on blood lipids
For experimental hyperlipidemia and experimental atherosclerosis models in rabbits fed with cholesterol foods, Xu Changqing has the effect of lowering serum total cholesterol and β-lipoprotein, and can reduce atherosclerosis and small arterial fat. Deposition, which shows Xu Changqing has a preventive effect on atherosclerosis.
Antimicrobial effect
Xu Changqing in vitro inhibition of Shigella, Staphylococcus aureus and so on.
Yu Zhu Pharmaceutical
Yu Zhu Pharmaceutical
Anti-inflammatory effect
Paeonol sulfonic acid sodium significantly inhibited formalin-induced foot swelling in rats. Paeonol significantly inhibited the ear swelling caused by xylene and carrageenan, egg white, formaldehyde, histamine, 5-HT, and bradykinin induced rat paw edema; Toxin-induced abdominal capillary permeability increased.
Other effects
Experiments show that: Paeonol has significant inhibitory effect on type II, III and IV allergic reactions. It does not significantly affect the formation of specific antibodies, but it can selectively inhibit the hemolytic activity of the classical complement pathway, and can also regulate cellular immune function. Paeonol has antioxidant effects and is more sensitive to calcium abnormal myocardial cells.
Compound Aminopyrine Phenacetin Tablets
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