"Jet casting" helps make artificial bones
Release date: 2014-05-12
The University of Tokyo in Japan has announced that its researchers have found that using injection molding machines that process resins and plastics, under certain temperature conditions, artificial bones that are expected to blend more easily with real bones can be produced.
After a comminuted fracture or removal of part of the bone during surgery, the patient needs to transplant the bone, but transplanting it by cutting the bones of other parts of the body will bring a great "burden" to the patient's body.
In addition, the common method for making artificial bones is to sinter the calcium phosphate, which is the main component of the bone, into a block or granule with a high temperature of 800 degrees Celsius or higher for further shaping and transplantation by a doctor. However, due to the high temperature sintering, the artificial bone after transplantation is not easily fused with the original bone.
In the study to solve the above problems, Zheng Xiongyi, a professor at the Graduate School of Engineering at the University of Tokyo, and colleagues found that if calcium phosphate is heated to 100 to 200 degrees Celsius to make it fluid, it is then poured into a metal mold using an injection molding machine. , you can make artificial bones in batches. Zheng Xiongyi said that in theory, this artificial bone made at relatively low temperature conditions is more likely to fuse with the patient's bone stump, but this inference has yet to be tested in clinical trials.
According to the plan, Zheng Xiongyi's research team will conduct clinical trials on the transplantation effect of this artificial bone this year. If the progress is smooth, the research results are expected to enter the practical stage after two to three years.
Original source: http://
Source: Bio 360
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