New blood test can predict prostate cancer invasiveness before surgery
New blood test can predict prostate cancer invasiveness before surgery
March 17, 2016 Source: Bio Valley
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Prostate cancer is one of the most common male cancers, with approximately 400,000 new cases each year in Europe. Surgery is an important way of treating prostate cancer, but the success of surgery depends on many factors. Now a new study from Milan shows that for patients undergoing radical prostatectomy, a simple blood test can predict the aggressiveness of the cancer before surgery.
Researchers from Milan have found that patients with hypogonadism (low levels of sex hormone testosterone) tend to have a higher Gleason index - which means that patients are still likely to have adverse consequences after treatment.
The researchers reviewed data from 1017 patients with radical prostatectomy and analyzed the association between hormone levels and the Gleason index, with 118 patients achieving the highest Gleason index. After correcting the age, the researchers found that levels of hypogonadism and sex hormone binding globulin were well predictive of patients who achieved the highest Gleason index.
The researchers said that this association can help patients predict outcomes before surgery, helping to find the aggressiveness of prostate cancer before surgery. However, it is still unclear whether hypogonadism increases the risk of high-grade prostate cancer in some way. If this relationship can be proved, treatment of hypogonadism may reduce the risk of high-grade prostate cancer, but it still needs a lot. Studies have shown that this relationship exists, and further research is needed to reveal the role of hormones in the development of prostate cancer.
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