Application of IKN emulsifier in silicone oil emulsification
Emulsification process
1 aqueous phase emulsification method
The aqueous phase emulsification method refers to an O/W type microemulsion prepared by dissolving an emulsifier in water and slowly stirring it while adding aminosilicone oil . This method is relatively simple to operate and is used in industry, generally at room temperature.
2 reverse phase emulsification
The reverse phase emulsification method refers to first mixing an emulsifier and an amino silicone oil, and then adding water to achieve a W/O conversion to O/W , that is, a phase inversion emulsification method, which is suitable for emulsification of a relatively high viscosity silicone oil. Doe Corning 's Gee conducted a detailed study of this approach.
In 1983 , Gee et al. applied for a patent for the preparation of a silicone oil microemulsion. The patent describes a method for preparing an organopolysiloxane emulsion having an average particle diameter of less than 300 nm and a microemulsion having an average particle diameter of less than 140 nm. An oil concentrate is prepared by mixing a polar group-containing polysiloxane, a surfactant, and a small amount of water ( Gee considers this oil concentrate to be a water-in-oil type microemulsion), and the oil concentrate is prepared. The oil-in-water microemulsion must rapidly disperse the concentrate into water, and the dispersion time is directly related to the particle size. The faster the dispersion, the smaller the average particle size of the obtained microemulsion. In general, if the concentrate is translucent, then only a translucent emulsion having a particle size of less than 300 nm can be obtained . If the concentrate is transparent, a transparent microemulsion having a particle size of less than 140 nm can be obtained . In industrial production, rapid dispersion requires different power agitators, such as ultrasonic mixing, kneading machines, colloid mills, homogenizers, and the like. As for the choice of surfactants, Gee believes that the main surfactants can be cationic, anionic and nonionic, but must be insoluble in silicone oils, and the HLB value must be greater than 8 . The cationic surfactant is preferably an ammonium salt, a sodium salt or a potassium salt, and the anionic surfactant is preferably a chloride salt. Nonionic surfactants are generally used, preferably in the Tregitol series (trimethyl decyl ethoxylate) and Triton series (octyl phenol ethoxylate ) of different hydrophilic lengths .
3- phase transition temperature method
Berthiaume et al. believe that at the phase transition temperature, the dissolution of the surfactant in the oil phase and the aqueous phase is balanced. At this time, the surfactant, the water phase and the oil phase are in the thermodynamic minimum free energy state, and the minimum free energy state corresponds. The minimum particle size of the emulsion. Therefore, it is proposed to carry out emulsification at a temperature slightly lower than the phase transition temperature and then rapidly stir to obtain a microemulsion having a particle diameter of only 10 to 25 nm . The microemulsion obtained by this method has a smaller particle size than other methods, but is industrially produced. Adjusting the temperature in the middle is not convenient.
Viral Transportation Medium Tube
Uses: used for the detection and sampling of influenza, hand, mouth, foot and other epidemic diseases
Inspection principle:
The combination of multiple antibiotics has broad-spectrum antibacterial and antifungal effects;
As a protein stabilizer, bovine serum albumin can increase the survival time and infection stability of the virus;
Buffers such as Hank's build a neutral environment, which helps to increase the survival time and infection stability of the virus;
Phenol red is an acid-base indicator, the discoloration area is 6.6 (yellow)~8.0 (red), and it is red at 7.2~7.4.
Steps:
1. According to the sampling requirements, use a sampling swab to collect samples.
2. Place the swab after collecting the sample into a sterile sampling tube.
3. Break the sampling swab rod that is higher than the sterile sampling tube.
4. Tighten the cap of the sterile sampling tube.
5. Label the sterile sampling tube with information as required.
For sample collection, transportation and storage.
Product advantages:
1. The virus discretion of the flocking swab is high to ensure the accuracy of the test results.
2. The samples are well sealed to ensure product transportation and safe storage.
3. Product instruction manual, product certificate
Product Details:
1. The product set includes a one-time Virus Sampling Tube (including preservation solution), a self-sealing bag, a sampling swab, and instructions.
2. Product specification: 100 sets/box, 8 boxes/box 3. Product weight: 0. 65kg/box, 13. 2kg/box
4. Packing size: 25. 5*23. 5*14. 5 boxes, 53*49*32/carton
Scope of application:
Work resumption testing, the best choice for large-scale population screening
Features:
1. Transport at room temperature, stably preserve viral RNA
2. Pre-packaged guanidine salt lysate can inactivate the new coronavirus, ensuring the safety of transportation and testing personnel 3. The large-capacity preservation solution can fully soak the swab head,
The sample size can be divided into three parts for testing and reserve samples respectively to meet the testing needs.
Scope of application:
Suspected cases, disease control testing, preferred by P3 laboratory
Viral Transportation Medium Tube,Sample Collection Tubes,Transport Nasal Swab With Tube,Virus Sampling Tube Nasopharyngeal Swab
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