Granulation method
Due to the different granulation methods, the tablet granulation method has:
(1) Extrusion granulation method: the medicinal material is added with a binder or a wetting agent or a thick immersion syrup, and is mixed into a soft material which is "kneaded into a mass, lightly squashed and dispersed", and is extruded through a sieve mesh. The granulation method is the granulation method which is currently used most in production.
(2) Wet mixing granulation method: a granulation method in which a medicinal material and an auxiliary material are co-located in a sealed container of a rapid stirring granulator, and the mixing, the soft material, the granulation and the spheronization are completed once.
(3) Spray rotary granulation method: the mixture of the powder and the auxiliary material is rotated in a coating pan or a suitable container, and the wetting agent or the adhesive is sprayed in a mist to make the powder adhere into small particles while heating to make water. Evaporate and roll until the granules are dry. This method is suitable for Chinese medicine semi-dip powder, extract powder or viscous drug fine powder granules.
(4) Fluidized spray granulation method: also known as "boiling granulation" or "one-step granulation method". The granulated powder is placed in the fluidization chamber of the fluidized spray granulation equipment, using air flow (temperature adjustable A method in which the suspension is fluidized and then sprayed with a wetting agent or a binder liquid to condense the powder into granules.
(5) Spray drying granulation method: the Chinese medicine concentrated liquid is atomized into a suitable size droplet by a special atomizer to be sprayed into the drying chamber, and dried in a hot air stream to obtain fine particles close to a spherical shape. The dry granules can be directly compressed or granulated by spraying.
Common granulation equipment: YK-60 small granulator, YK-160 large granulator
We could undertake custom development,custom manufacturing for various organic chemicals,special chemicals intermediates and raw materials, ranging from g, kg to 100-ton-level clinical and mass production products.Volsen not only owns more than 10 years commercial production experiences of common products, but also owns a professional custom synthesis team, it makes up for developing issue of production team,production experiences issue of research team. realized the most efficient combination of production and R&D. We can conduct process optimization to the technology provided by our customers, as well as carry out new process development for product provided by them.
The target of Custom synthesis
1. Provide customers with integrated services throughout the life cycle of the product in areas such as agricultural chemicals, pharmaceuticals chemicals.
2. Production enlargement, Continuous Process development
3. Continuous quality improvement, cost reduction and efficiency optimization.
The Advantage of Custom synthesis
1.High efficient, rich experience and full of innovative professional R & D team.
2.Advanced research and development equipment, flexible pilot plant,improved production facilities
3.Professional project management personnel, a sound project management system.
4.The tailored customized production help customers to reduce the cost of money and time.
Mode of Custom synthesis
1.Conduct process optimization to the technology provided by our customers
2. Carry out new process development for product provided by them.
The process of customized business:
1) Complete the project analysis and respond to customers in three days after received a single customer consultation;
2) Two parties confirm the quality specification as the final quality standards.
3) R&D department starts to research, synthesis.Give weekly report to customer about project progress.
4) Customer confirms the sample, later,we provided details of production schedule.
5) Two parties signed the contract.
6) After finished, QA department make a analysis.
7) Customer acceptance of products by qualified finished.
Confidential Commitment
Keep Strictly confidential of client projects is one of our business criteria, we will put the confidentiality on the height of strategic development. We conduct strictly confidentiality measures and workflows.If necessary, may enter into a confidentiality contract. We are willing to work closely with customers at home and abroad to develop the production of new chemical products.No matter what the issue.We are ready to serve you faithfully.
Chemical Product Customization, Customized Pharmaceutical Products, Pharmaceutical Customization
Taizhou Volsen Chemical Co., Ltd. , https://www.volsenchem.com