The world's first computer-assisted 4D printed breast reconstruction was successful in China

The Fourth Military Medical University Xijing Hospital reported on the 6th that the hospital successfully implemented the world's first computer-assisted 4D printed biodegradable material filler breast reconstruction surgery, bringing new reconstruction methods for breast cancer mastectomy patients.

In August 2016, Zhang Xue (pseudonym) suffering from breast cancer was treated at Xijing Hospital. At that time, the size of the tumor exceeded 6 cm. Although neoadjuvant chemotherapy was implemented, only full breast resection was performed. Experts decided to implement a computer-assisted 4D printed biodegradable material filler breast reconstruction surgery.

Before the operation, the doctor first performed a thin-layer breast MRI scan, and accurately acquired tumor and breast image information through MRI, and performed three-dimensional reconstruction and simulated resection on the computer. On this basis, the size of the filler is precisely designed according to the tissue defect that is simulated and the one-to-one 3D printing of the defect is performed.

On the day of the operation, the doctor performed a large-scale resection of the left breast cancer and axillary lymph node dissection based on the results of the computer simulation. Then, a pre-designed 4D printed biodegradable material filler was implanted in the defective breast tissue. Breast reconstruction. The patient recovered well after surgery and was discharged on the third day. The patient also received radiotherapy routinely. After several re-examinations, the implants were gradually shaped, with good tissue compatibility, and autologous fibrous vascular tissue began to grow.

The bio-filling material used in this application belongs to the category of “4D”, adding the time dimension, that is, by changing the molecular weight of the structure and material, the filler can be deformed and degraded within a set time to avoid leaving foreign matter in the body. The biodegradable material filler implanted for Zhang Xue can be deformed and degraded within one and a half to two years. During this time, the autologous fibrous tissue will gradually grow into the implant and eventually replace the implant completely. , to ensure the shape of the breast.

According to experts, the successful implementation of this procedure has greatly broadened the indications for breast-conserving surgery for breast cancer, avoiding the huge trauma of autologous breast reconstruction, and the complications caused by the application of silicone prosthesis, and the filling can be accurately individualized. Design, will become a new breast reconstruction.

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