Diagnostic value of repeated nerve electrical stimulation and fatigue test for systemic myasthenia gravis
Release date: 2016-03-31
Recently, neurology researchers at the Third Affiliated Hospital of Southern Medical University published a paper to investigate the clinical value of repetitive nerve stimulation (RNS) and fatigue testing in patients with systemic myasthenia gravis (MG). . The study pointed out that RNS is an effective method for diagnosing patients with systemic MG. Multi-muscle comprehensive statistics and fatigue test methods can improve the positive rate of diagnosis. The article was published in the 2015 issue of the South China Journal of National Defense Medicine.
Low-frequency and high-frequency RNS were performed on the orbicularis oculi, elbow muscle, small finger muscle, and deltoid muscle of 62 patients with systemic MG admitted to the hospital. RNS was performed after muscle tonic contraction, and 4 muscles were diagnosed at different frequencies. Rate and positive rate of diagnosis before and after fatigue testing.
The low-frequency RNS positive rate of orbicularis, elbow and deltoid muscle was significantly higher than that of high-frequency RNS. The difference between the two was statistically significant (P<0.05). The difference between low-frequency stimulation and high-frequency stimulation of small finger muscle There was no statistical significance (P>0.05). The positive rate of orbicularis, elbow and deltoid muscles after fatigue test was significantly higher than that before fatigue test, the difference was statistically significant (P<0.05), small finger muscle fatigue test There was no significant difference in the positive rate between the two groups (P>0.05). The positive rate of the four muscles was significantly higher than that of the single muscle. The difference was statistically significant (P<0.05).
Source: Wanfang Data
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