L-Carnitine is essential in the utilization of fatty acids and in transporting metabolic energy.
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Eating sugar or slowing tumor growth
2024-11-27 20:00:56
Eating sugar or slowing tumor growth
November 22, 2018 Source: Chinese Journal of Science and Technology
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];A British research team recently said that taking monosaccharide mannose alone or in combination with chemotherapy drugs can slow tumor growth in mice. The research is promising, but further research is needed to verify it. Related papers are published online in Nature.
Many tumors undergo metabolic changes that show an increase in glucose uptake, which raises the question of whether taking different types of sugar can affect tumor growth.
Kevin Ryan of the British Cancer Research Center and colleagues studied the effects of mannose on tumor cell growth. They report that mannose slows tumor cell growth and suggests that mannose may interfere with glucose metabolism. In addition, the use of chemotherapeutic drugs cisplatin or doxorubicin to take mannose significantly increased tumor cell death. The researchers allowed tumor mice to take mannose by tube feeding (3 times a week) and drinking water (continuously) and found that the therapy was well tolerated and appeared to slow tumor growth either alone or in combination with doxorubicin. .
On the other hand, the sensitivity of tumor cells to mannose is associated with lower levels of phosphomannose isomerase (PMI). The researchers tested PMI levels in cells from different human tumors (ovarian, kidney, breast, prostate, and colorectal) and the results were mixed. Of particular note is that colorectal tumors have lower levels of PMI, which means they may be more sensitive to mannose. Tumors were significantly reduced in mice with colorectal cancer after taking mannose.
Researchers say mannose therapy may represent a simple and safe way to target multiple tumor growth.
Application & Function:
Application & Function:
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CAS541-15-1 Hot Sale High Quality L-Carnitine Powder
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Product name:
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L-Carnitine
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Appearance:
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White crystalline powder
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Purity:
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99%min
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CAS:
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541-15-1
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Molecular Formula:
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C7H15NO3
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Molecular Weight:
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161.20
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EINECS:
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208-768-0
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Introduction:
The body produces carnitine in the liver and kidneys and stores it in the skeletal muscles, heart, brain, and other tissues. But its production may not meet the needs under certain conditions such as increased energy demands and therefore it is considered a onditionally essential nutriention. There are two forms (isomers) of carnitine, viz. L-carnitine and D-carnitine, and only the L-isomer is biologically active.
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