Former Baidu executives research and develop the world's first AI screening fundus camera, has launched more than 200 primary medical institutions

In the field of fundus screening, Beijing Zhizhen Internet Technology Co., Ltd. launched the world's first handheld portable "smart screening fundus camera", which is positioned for the grassroots doctors, the shooting process is simpler, portable and intelligent.

According to founder Dai Liming, this smart device is about to be put into 100 primary medical institutions. The plan for 2019 is to empower thousands of primary health care services to help more grassroots eye health management services.

Dai Liming worked in Baidu for ten years and served as Baidu's commercial department executive. The tens of millions of A rounds of financing were also led by Baidu. He said that it was this cooperation with the old club that brought a technical turning point to the truth. This is also the only medical company that was invested by Baidu in the early AI track.

At the same time, last year, the company completed the tens of millions of Pre-A rounds of financing jointly led by Baidu and Shengjing Jiacheng, Meihua Angel, Huayao Capital, Huajian Capital and Investment, and Evolution Capital as the exclusive financial advisor.

So how did this AI fundus screening camera develop successfully? How does the filming work? What is the highlight of it? The arterial network interviewed Ding Lim, one of the true CEOs and founders.

Integrating multiple technologies into one, intelligent hardware solves three major pain points at the grassroots level

For a long time, “not portable”, “difficult to film” and “difficult to read” are the three major pain points of traditional fundus screening work in grassroots areas. "If there is a kind of 'fool camera' type of screening equipment that is easy to operate, it is good to know if there is any problem with the eye." This is the common aspiration of many grassroots doctors.

Introduced by Dawning, the intelligent screening fundus camera is specially designed for the fundus screening of primary doctors. It integrates intelligent fundus photography and disease screening. It is jointly developed by 100 research and development personnel for two years to meet the needs of grassroots doctors in screening scenes. Core needs. It has three core technologies.

First of all, smart focus technology. He said that the biggest problem when developing intelligent screening of fundus cameras is how to intelligently control the light path. They want light to pass through the pupil to make a 45-degree angle to observe the human eye, so the choice of light source is a very critical issue.

According to Dai Liming, there is a great risk of divergence at the grassroots level, so the mode of exemption is the best, that is, the light is thrown into the eye without dilation. They worked with their partners on the light path and switched to the near-infrared mode. At the same time, through the intelligent focus technology, the resolution is adjusted in real time, so that the smart camera can get the near-infrared light into the fundus in the shortest time and the best path, thereby obtaining high-definition images.

The second is intelligent tracking technology. Because the fundus map needs to meet the diagnostic criteria, in order to ensure the stable collection of key areas of the fundus, the image is semantically recognized and tracked in real time to ensure that key information in the fundus image can be captured. This is what many grassroots doctors The main link of traditional equipment is difficult to learn. With intelligent tracking technology, the camera can assist the grassroots doctor in accurately locking and shooting.

The third is intelligent exposure technology. After the machine is aimed at the eye, the button is clicked and the entire acquisition process takes a few hundred milliseconds. However, in these hundreds of milliseconds, many situations may occur, the doctor shakes hands, or the patient's eyes move, and the images obtained are still inconsistent with the standard, so the camera can only perform real-time image quality evaluation with a quality of 90 points. Above, the camera automatically captures the shot to ensure a high pass rate of the final fundus image.

Finally, the intelligent fundus camera is equipped with 4G and WI-FI communication capabilities, data can be pushed to the cloud in real time, parsed by the AI-assisted algorithm engine and finally reviewed by the doctor, and a medical-level screening report can be issued within 5 minutes. This not only improves the patient's medical experience, but also greatly improves the medical efficiency for the primary doctors and facilitates the follow-up service.

Bundle hardware, apply to the grassroots, and gradually build a business closed loop

This device also brings a change in business model to the true. Dai Ding said that based on the "intelligent fundus screening fundus camera", at the beginning of this year, Zhizheng Internet locked in two strategies. The first strategy is how to commercialize. Dai Liming served as the head of Baidu's business department, so he knew how to build business logic.

There are three characteristics of full commercialization. The first is demand, the demand is fundamental, and the human needs for health are great. The second point is whether the enterprise can reflect its own business value. Simply put, the enterprise provides services to consumers and meets their needs. Consumers are willing to exchange equivalent services for this service. The medical insurance provider also Willing to pay for it. The third point is whether you can turn this commercial part into a profit.

In this, the profit level is a key point. If the application scenario of the device cannot be opened, then no profit can be formed. So start from the second point, bundle with the hardware company and make your own hardware.

However, the cost of bundling with hardware is very high. In the case of high cost, it is really necessary to build a marketing team. Therefore, in the future, the profit must be realized, and the cost must be pressurized. In the process of pressing down, the first is to reduce the price of equipment, and the second is to increase the efficiency of the whole operation in the process of empowering the grassroots. In this way, the equipment can be better promoted. Under this system, the company and the customer will create a win-win situation. The current strategy is to first lay this equipment to the primary health care institutions for free, and then divide them.

On the specific application mode of the “smart screening fundus camera” equipment, Dai Liming said that the cooperation with primary medical institutions is still mainly in the model establishment stage. At present, more than 10 primary medical institutions have begun to use this equipment, contracted medical care. There are almost 200 institutions. The number of medical institutions that put the equipment into use before the Spring Festival is expected to reach more than 100. The plan for 2019 is to reach 1,000.

Returning to the beginning of the business: improving the accuracy of diagnosis and keeping the light of the grassroots

“Brightness is very common for healthy people, but it is a luxury for patients.” This is why Dawn chose to start an ophthalmology business.

That was May of 2016. On that day, Dai Liming volunteered to accompany the same pedestrian to the clinic in Suining County, Hunan Province. In the clinic, an eleven-year-old girl appeared, closed her eyes and was helped by her father. The medical staff checked it and used traditional fundus screening equipment. The Beijing expert conducted a remote diagnosis on it, and the result was a lifelessness, that is, complete blindness.

This case shocked Dai Liming. After repeated confirmation with the Beijing experts, the result was the same as the first time. Experts explained that this little girl has a genetic history of congenital glaucoma, but because it was not discovered in time, the condition deteriorated and led to blindness. If you can find this patient two years earlier, it will not be the case.

The girl was very calm and listened to the expert's diagnosis. She didn't cry and didn't make trouble. She went out with her father's help.

Having said that, the eyes of Dai Liming are moist. This incident has deeply shocked him. Since then, he has been thinking about it. During Baidu’s ten-year career, he has been exposed to so many technologies and resources. Can he contribute to these ordinary people?

On that day, because of the large number of people, the clinic that should have ended at 12:30 was extended to one and a half. After the clinic, they went out and found that the local patients were waiting outside. The old people expressed their gratitude with their hands together and watched them leave.

It was at that moment that Dai Dawn saw the value and significance of doing this.

"Intelligent screening, guarding the light", there are such eight words on the official website. Dai Ding told us that this was the day after the end of the clinic, on the way back, looking at the drizzle outside the window, he wrote these eight words. These eight words have become a professional creed.

"If you can let these patients keep their light because of your products and services, then they are benefiting them," said Dawn.

Previously, Dai Liming took the equipment as a volunteer to the grassroots doctors in Xuyong County, Sichuan Province, a state-level poverty-stricken county. During the screening process, they met an old man. The old man’s eyes need surgery. The operation only costs two thousand dollars, but Dai Liming and the staff mobilized for three days. The old man insisted on not performing surgery. The old man told them that his family's economic situation is not good. Although he can take out these two thousand dollars, he is not willing to spend it on his coveted person and insist on leaving his granddaughter to pay tuition.

Dai Liming said that at that moment he thought why the disease cost two thousand dollars to cure, not two hundred dollars. It is because these conditions cannot be detected early in the early stage, leading to deterioration in the later stage, and can only be treated with more complicated and more expensive methods.

He talked with the grassroots doctor about the difficulties at the grassroots level. The doctor’s words touched him. “In fact, we are a small grassroots doctor, but we are very busy every day, and we are very eager to learn advanced techniques and methods. Why every day? Is it so hard to work? Because our idea is that saving a person is equivalent to saving a family. Because if everyone does not save, then no one can save them. It is because we are willing to join this. In the industry, everyone can make a difference and take the lead. This can be done."

These experiences are the key factors in the true internal driving force. After this, Dai Liming set the goal of the "service base". If you can put money into the smart products, improve performance and indicators, make the disease discovery process simpler, and make the image accuracy higher, the meaning will be greater, this is the true value.

Start with ophthalmology, lock the grassroots, and improve the capacity building of the endocrine department at the grassroots level

In order to realize the eye health screening service for the generalized diabetic population in more grassroots areas, at the press conference, 200 special intelligent fundus screening cameras were donated to the China Geriatric Care Association to assist the endocrinology departments in each county. Efficient, high quality sugar mesh screening.

Professor Liu Yuanli, Dean of Peking Union School of Public Health and President of China Association of Geriatric Care, said that in many primary hospitals, the endocrinology department is the first department to conduct sugar net screening, but the proportion of sugar net screening ability is very low. Intelligent screening of fundus cameras into the grassroots endocrine department not only solves the problem of filming, but also solves the diagnosis problem. It is hoped that these smart devices can benefit more grassroots patients and accumulate more experience in diabetes prevention and control management in the country.

Dai Ding said that the penetration rate of smart machines will be higher, including every primary hospital, family doctor, and even pharmacies and eye shops. In the future, it is even possible to implement devices into the home, so that ordinary people can operate at home, and reports can be sent to the cloud for AI processing and remote interpretation. By that time, eye health screening and management will benefit everyone more and have more social significance and value.

This device empowers data entry, even if the primary doctor can use it simply and efficiently. This is the core appeal and core competitiveness of this product.

As the data gradually accumulates to a higher level, all the knowledge systems in the bio-information information need to be clustered under one point, which is scientific discovery. And this scientific discovery is the correlation between a fundus image and clinical. On behalf of Dawn, the scientific discovery will open up a great enterprise once it is opened from the bottom of the eye. He also expects that a large number of related applications will be opened up to around 2020, including equipment into the home.

In the future, AI will be applied to more diseases, and the original fundus screening data will be analyzed for big data. Dai Liming tells us that the size of the database is now the world's leading, and this is only adult. In September this year, the country's leading neonatal fundus image database was established, and the newborn can pass the fundus screening test. A variety of eye diseases can be cured, and most of these diseases can be cured by early screening and early intervention.

In parallel with this work, the "smart screening fundus camera" device is launching a global medical certification. If the application is approved, this device will open the international market for the real thing.

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