The efficacy and side effects of Codonopsis
Codonopsis is sweet, flat, and has the effect of supplementing qi, replenishing qi, producing fluid, nourishing blood, invigorating spleen, and calming. It is suitable for weak spleen and stomach, loss of qi and blood, body fatigue, low appetite, thirst, and chronic diarrhea. . The following describes the efficacy and side effects of Codonopsis.
The effect of Codonopsis
The main effect of Codonopsis is qi. The most suitable for normal fatigue, lack of energy. Voice-poor, self-conscious, shortness of breath, lung weakness caused by a little activity. Focus on the spleen and stomach qi deficiency of people, limb weakness, loss of appetite, loose stools, but also should use Codonopsis. Commonly used parties involved in Atractylodes macrocephala, Poria, Zhigancao compatibility, this is the famous recipe for qi and spleen Sijunzitang. Lung and temper are empty, and it is appropriate to use the party to participate in Astragalus, Atractylodes, Poria, Citrus, Angelica, Cimicifuga, Bupleurum, Zhigancao, ginger, jujube compatibility, which is a famous Bu Zhong Yi Qi Tang.
Codonopsis qi can nourish blood, which is a major feature of it. Therefore, qi and blood deficiency, shortness of breath, heart palpitations, fatigue, pale, dizziness, bad appetite, loose stools, and people who are prone to catch cold, should also take Codonopsis. Experiments have shown that Codonopsis can increase red blood cells and increase hemoglobin, so it is beneficial for patients with anemia to consume Dangshen. Due to the decline of white blood cells caused by chemotherapy and radiation therapy, taking Codonopsis also has the effect of promoting the recovery of white blood cells.
In recent years, it has also been found that the party's involvement in Astragalus and Atractylodes can reduce the urinary protein in patients with chronic nephritis.
Pharmacological effects
1. The role of the central: Codonopsis decoction against strychnine-induced mouse convulsions, prolonged the time of convulsions, prolong the survival time of mice, but also have anti-convulsive effects. Codonopsis decoction can significantly counteract scopolamine-induced memory impairment in mice; it also has an antagonistic effect on alcohol-induced impairment of memory in mice.
2. The role of cardiovascular: alcohol immersion and aqueous extracts have antihypertensive effect, its antihypertensive effect is due to peripheral vasodilation caused by ethanol immersion fluid on isolated iliac heart inhibition.
3. Effects on Blood: Dangshen water-solubilized substances have an inhibitory effect on platelet aggregation induced by ADP in rats. Commercial Codonopsis can significantly increase red blood cells in rabbits, while white blood cells decrease significantly.
4. Anti-ulcer effect: Codonopsis has anti-gastric mucosal damage and enhances gastric mucosal cell protection. 〔Antiulcer effect Codonopsis n-butanol neutral extract intragastrically administers prophylactic protection against stress, pyloric ligation, indomethacin and aspirin experimental gastric ulcer in rats, indomethacin and aspirin induced rat stomach The mucosal prostaglandin E2 (PGE2) and amino hexose decreased significantly and the gastric acid secretion was inhibited. The Dangshen extract could significantly increase the content of PGE2 in normal rats, and the prostacyclin (PGI2) Both thromboxane A2 (TXA2) levels were reduced, but TXA2 decreased significantly, and the ratio of PGI2 to TXA2 increased. It is believed that the resistance of Dangshen against gastric mucosal injury is related to the enhancement of gastric mucosal cell protection. ]
5. Effects on immune function: Codonopsis decoction can significantly promote the biosynthesis of ConA-activated splenic lymphocytes DNA and protein, promote the optimal concentration of DNA synthesis to 100μg/ml, to leukocyte medium-2 (IL-2) The production also has a significant enhancement. The phagocytic function of the mouse reticuloendothelial system is also enhanced.
6. Anti-fatigue and anti-hypoxic effects: Codonopsis decoction can prolong the weight-bearing swimming time of mice, and can significantly prolong the survival time of hypoxic mice.
Codonopsis side effects
Codonopsis is an qi-supplemented drug, and there are basically no side effects of normal drug use. However, if the drug is used for a long time or the amount is too large, it will cause too much qi and it will hurt the body and produce dryness.